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Metabolic engineering of methanotrophs and its application to production of chemicals and biofuels from methane
Author(s) -
Lee Ok Kyung,
Hur Dong Hoon,
Nguyen Diep Thi Ngoc,
Lee Eun Yeol
Publication year - 2016
Publication title -
biofuels, bioproducts and biorefining
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.931
H-Index - 83
eISSN - 1932-1031
pISSN - 1932-104X
DOI - 10.1002/bbb.1678
Subject(s) - biofuel , metabolic engineering , methane , biochemical engineering , raw material , commodity chemicals , production (economics) , chemical industry , environmental science , waste management , engineering , chemistry , environmental engineering , catalysis , economics , biochemistry , organic chemistry , enzyme , macroeconomics
Methane‐assimilating bacteria, methanotrophs, can play an important role in producing various value‐added chemicals and biofuels from methane, which is considered a next‐generation carbon feedstock. The capability to engineer the metabolic pathway of methanotrophs is a key success factor for enhancing methane‐to‐product conversion efficiency. Recently, OMICS studies on several model methanotrophs have been conducted and provided strategies to engineer methanotrophs. Here, we present a review on the current progresses and future prospects of metabolic engineering of methanotrophs and its application to chemical and biofuel production from methane. © 2016 Society of Chemical Industry and John Wiley & Sons, Ltd