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Recent advances in neurogenic and neuroprotective effects of curcumin through the induction of neural stem cells
Author(s) -
Heidari Shadi,
Mahdiani Sina,
Hashemi Maryam,
Kalalinia Fatemeh
Publication year - 2020
Publication title -
biotechnology and applied biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.468
H-Index - 70
eISSN - 1470-8744
pISSN - 0885-4513
DOI - 10.1002/bab.1891
Subject(s) - curcumin , neuroprotection , neural stem cell , stem cell , neuroscience , neurogenesis , pharmacology , medicine , biology , microbiology and biotechnology
Curcumin is extensively used in the prevention and treatment of various diseases. Recently, growing attention has been paid to the use of curcumin as a neurogenic and neuroprotective agent. This review study is aimed to collect and categorize the recent findings regarding the effects of curcumin on various neurological diseases through the induction of neural stem cell proliferation and differentiation. In addition, we have discussed the molecular mechanisms modulated by curcumin that contribute to this efficacy and have summarized the recent advancements in the novel delivery strategies used to improve the induction of neural stem cells by curcumin.