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Insights on the current status and advancement of diabetes mellitus type 2 and to avert complications: An overview
Author(s) -
Chung IllMin,
Rajakumar Govindasamy,
Subramanian Umadevi,
Venkidasamy Baskar,
Khanna Venkatesan Gopiesh,
Thiruvengadam Muthu
Publication year - 2020
Publication title -
biotechnology and applied biochemistry
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.468
H-Index - 70
eISSN - 1470-8744
pISSN - 0885-4513
DOI - 10.1002/bab.1853
Subject(s) - type 2 diabetes mellitus , insulin resistance , diabetes mellitus , type 2 diabetes , disease , medicine , insulin , intensive care medicine , metabolic disorder , bioinformatics , endocrinology , biology
Abstract Type 2 diabetes mellitus (T2DM) is an endocrine metabolic disorder, occurring worldwide due to aging, advancement in lifestyle by modernization. T2DM is characterized by higher levels of glucose in the blood due to unresponsive secretion of pancreatic insulin and insulin activity or altogether. T2DM is regarded as a powerful genetic susceptible disease that leads to high risk with insulin resistance and β‐cell dysfunction. To manage and overcome type 2 diabetes, physical activity, diet strategies, and other therapeutic medications along with usage of antiglycemic agents are developed and attempted appropriately. In the present review, attention has been focused on the understanding of T2DM outcomes, complications with possible management strategies, and pathophysiology of T2DM. Further, a detailed note on antiglycemic agents in use and other possible drugs of choice was discussed in the light of current preventive strategies are presented in this review.