Premium
A pharmacogenetic study of escitalopram in autism spectrum disorders
Author(s) -
Owley Thomas,
Brune Camille W.,
Salt Jeff,
Walton Laura,
Guter Steve,
Ayuyao Nelson,
Gibbons Robert D.,
Leventhal Bennett L.,
Cook Edwin H.
Publication year - 2010
Publication title -
autism research
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.656
H-Index - 66
eISSN - 1939-3806
pISSN - 1939-3792
DOI - 10.1002/aur.109
Subject(s) - escitalopram , irritability , genotype , autism spectrum disorder , serotonin transporter , autism , psychology , citalopram , psychiatry , clinical psychology , medicine , genetics , cognition , anxiety , biology , gene , antidepressant
To determine the effect of serotonin transporter polymorphism promoter region (5-HTTPLR) genotypic variation (low, intermediate, and high expression groups) on response to escitalopram treatment of children and adolescents with autism spectrum disorders (ASDs).