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Vancomycin‐Functionalized Porphyrinic Metal‐Organic Framework PCN‐224 with Enhanced Antibacterial Activity against Staphylococcus Aureus
Author(s) -
Chen LiJian,
Liu YaoYao,
Zhao Xu,
Yan XiuPing
Publication year - 2021
Publication title -
chemistry – an asian journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.18
H-Index - 106
eISSN - 1861-471X
pISSN - 1861-4728
DOI - 10.1002/asia.202100546
Subject(s) - staphylococcus aureus , antibacterial activity , antimicrobial , vancomycin , chemistry , metal organic framework , microbiology and biotechnology , bacteria , organic chemistry , biology , adsorption , genetics
Abstract A vancomycin (Van) modification strategy on a porphyrinic metal‐organic framework (MOF) PCN‐224 is presented. The obtained Van‐PCN‐224 gives the combined advantages of porphyrinic MOF and Van with high photosensitive activity and excellent targeted antibacterial activity against Staphylococcus aureus . The features make Van‐PCN‐224 promising for antimicrobial therapy.