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Near‐Infrared‐II Semiconducting Polymer Dots for Deep‐tissue Fluorescence Imaging
Author(s) -
Gupta Nidhi,
Chan YangHsiang,
Saha Sampa,
Liu MingHo
Publication year - 2021
Publication title -
chemistry – an asian journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.18
H-Index - 106
eISSN - 1861-471X
pISSN - 1861-4728
DOI - 10.1002/asia.202001348
Subject(s) - autofluorescence , fluorescence , fluorescence lifetime imaging microscopy , materials science , polymer , nanotechnology , brightness , optical imaging , nanoparticle , near infrared spectroscopy , biophysics , optics , biology , physics , composite material
Fluorescence imaging, particularly in the NIR‐II region (1000–1700 nm), has become an unprecedented tool for deep‐tissue in vivo imaging. Among the fluorescent nanoprobes, semiconducting polymer nanoparticles (Pdots) appear to be a promising agent because of their tunable optical and photophysical properties, ultrahigh brightness, minimal autofluorescence, narrow‐size distribution, and low cytotoxicity. This review elucidates the recent advances in Pdots for deep‐tissue fluorescence imaging and the facing future translation to clinical use.