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Synthesis of Sulfonylated Heterocycles via Copper‐Catalyzed Heteroaromatization/Sulfonyl Transfer of Propargylic Alcohols
Author(s) -
Chen Xinyi,
Shatskiy Andrey,
Liu JianQuan,
D. Kärkäs Markus,
Wang XiangShan
Publication year - 2021
Publication title -
chemistry – an asian journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.18
H-Index - 106
eISSN - 1861-471X
pISSN - 1861-4728
DOI - 10.1002/asia.202001126
Subject(s) - sulfonyl , isocyanide , catalysis , chemistry , copper , combinatorial chemistry , organic chemistry , alkyl
An unprecedented copper‐catalyzed heteroaromatization/sulfonyl transfer of propargylic alcohols with isocyanide has been developed. 3‐Sulfonyl benzofurans and indoles were produced under Cu(I) catalysis in good to high yields. The developed catalytic methodology provides controlled, modular, and facile access to sulfonyl benzoheterocycle scaffolds.