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Indole‐ N ‐Carboxylic Acids and Indole‐ N ‐Carboxamides in Organic Synthesis
Author(s) -
Zeng Linwei,
Lin Yuxin,
Cui Sunliang
Publication year - 2020
Publication title -
chemistry – an asian journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.18
H-Index - 106
eISSN - 1861-471X
pISSN - 1861-4728
DOI - 10.1002/asia.201901806
Subject(s) - indole test , chemistry , organic synthesis , organic chemistry , combinatorial chemistry , molecule , catalysis
Indoles are ubiquitous structures that are found in natural products and biologically active molecules. The synthesis of indoles and indole‐involved synthetic methodologies in organic chemistry have been receiving considerable attention. Indole‐ N ‐carboxylic acids and derived indole‐ N ‐carboxamides are intriguing compounds, which have been widely used in organic synthesis, especially in multicomponent reactions and C−H functionalization of indoles. This Minireview summarizes the advances of reactions involving indole‐ N ‐carboxylic acids and indole‐ N ‐carboxamides in organic chemistry, and discusses the synthetic potential and perspective of this field.