A Cascade Synthesis of Hetero‐arylated Triarylmethanes Through a Double 5‐ endo ‐dig Cyclization Sequence | Zendy

Paluru Dilip K. | Zendy; Mahesh Sriram | Zendy; Ahmad Feroz | Zendy; Vijaya Anand Ramasamy | Zendy

AI Assistant Blog Pricing

Home ZAIA Blog

Premium

A Cascade Synthesis of Hetero‐arylated Triarylmethanes Through a Double 5‐ endo ‐dig Cyclization Sequence

Author(s) -

Paluru Dilip K.,

Mahesh Sriram,

Ahmad Feroz,

Vijaya Anand Ramasamy

Publication year - 2019

Publication title -

chemistry – an asian journal

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.18

H-Index - 106

eISSN - 1861-471X

pISSN - 1861-4728

DOI - 10.1002/asia.201900960

Subject(s) - dig , chemistry , indolizine , cascade , combinatorial chemistry , sequence (biology) , medicinal chemistry , stereochemistry , computer science , chromatography , biochemistry , computer security

A sequential two‐step method for the synthesis of hetero‐arylated triarylmethanes through a Ag‐catalyzed sequential double cyclization–nucleophilic addition cascade is described. This methodology basically involves an initial 5‐ endo ‐dig cyclization of o ‐alkynyl anilines to provide 2‐substituted indole derivatives, which then react with 2‐(2‐enynyl)‐pyridines to afford indolizine‐containing unsymmetrical triarylmethanes through another 5‐ endo ‐dig cyclization.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research