Zinc‐Catalysed Hydroboration of Terminal and Internal Alkynes | Zendy

Mandal Souvik | Zendy; Mandal Sayantan | Zendy; Geetharani K. | Zendy

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Zinc‐Catalysed Hydroboration of Terminal and Internal Alkynes

Author(s) -

Mandal Souvik,

Mandal Sayantan,

Geetharani K.

Publication year - 2019

Publication title -

chemistry – an asian journal

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.18

H-Index - 106

eISSN - 1861-471X

pISSN - 1861-4728

DOI - 10.1002/asia.201900839

Subject(s) - hydroboration , chemoselectivity , regioselectivity , chemistry , catalysis , zinc , terminal (telecommunication) , trifluoromethanesulfonate , organic chemistry , combinatorial chemistry , medicinal chemistry , computer science , telecommunications

A regioselective hydroboration of alkynes has been developed by using commercially available zinc triflate as a catalyst, in the presence of catalytic amount of NaBHEt 3 . The reaction tolerates a wide range of terminal alkynes having several synthetically useful functional groups and proceeds regioselectively to furnish hydroborated products in moderate to excellent yields. This system shows moderate chemoselectivity towards terminal C≡C bond over terminal and internal C=C bond and internal C≡C bond.

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