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Unsymmetrical Disulfides Synthesis via Sulfenium Ion
Author(s) -
Parida Amarchand,
Choudhuri Khokan,
Mal Prasenjit
Publication year - 2019
Publication title -
chemistry – an asian journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.18
H-Index - 106
eISSN - 1861-471X
pISSN - 1861-4728
DOI - 10.1002/asia.201900620
Subject(s) - umpolung , electrophile , chemistry , yield (engineering) , catalysis , combinatorial chemistry , iodine , ion , in situ , organic chemistry , nucleophile , materials science , metallurgy
An umpolung approach for the synthesis of unsymmetrical disulfides via sulfenium ion is reported. In situ generated electrophilic sulfenium ion from electron‐rich thiols reacted with second thiols to yield unsymmetrical disulfides. Using an iodine catalyst and 4‐dimethylaminopyridine (DMAP)/water as promoter, the target syntheses were achieved in one pot under aerobic condition.