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Nazarov Reagent: New Role for the [4+2] Domino Benzannulation Reaction to Construct Polysubstituted Benzenes
Author(s) -
Chang Meijia,
Huang You
Publication year - 2019
Publication title -
chemistry – an asian journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.18
H-Index - 106
eISSN - 1861-471X
pISSN - 1861-4728
DOI - 10.1002/asia.201900590
Subject(s) - reagent , domino , construct (python library) , chemistry , combinatorial chemistry , organic chemistry , reaction conditions , catalysis , computer science , programming language
A new role for the Nazarov reagent was revealed in the [4+2] benzannulation reaction, and delivered a series of polyfunctional benzenes in high yields under mild conditions. This metal‐free process not only expanded the application of the Nazarov reagent in organic synthesis, but also provided a new, efficient way to construct polyfunctional benzenes.