TFAA‐Catalyzed Annulation Synthesis of Spiro Pyrrolo[1,2‐ a ]quinoxaline Derivatives from 1‐(2‐Aminophenyl)pyrroles and Benzoquinones/Ketones | Zendy

Ni Jixiang | Zendy; Jiang Yong | Zendy; Qi Zhenjie | Zendy; Yan Rulong | Zendy

Premium

TFAA‐Catalyzed Annulation Synthesis of Spiro Pyrrolo[1,2‐ a ]quinoxaline Derivatives from 1‐(2‐Aminophenyl)pyrroles and Benzoquinones/Ketones

Author(s) -

Ni Jixiang,

Jiang Yong,

Qi Zhenjie,

Yan Rulong

Publication year - 2019

Publication title -

chemistry – an asian journal

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.18

H-Index - 106

eISSN - 1861-471X

pISSN - 1861-4728

DOI - 10.1002/asia.201900567

Subject(s) - quinoxaline , annulation , chemistry , catalysis , nucleophile , combinatorial chemistry , medicinal chemistry , nucleophilic addition , organic chemistry

A metal‐free trifluorosulfonate anhydride (TFAA)‐catalyzed strategy for the synthesis of spiro pyrrolo[1,2‐a]quinoxalines from 1‐(2‐aminophenyl)pyrroles and benzoquinones/ketones has been developed. With this general method, spiro pyrrolo[1,2‐a]quinoxalines have been accessed via nucleophilic addition and cyclization. This reaction exhibits good functional group tolerance, and a wide range of products are obtained in moderate to good yields.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research