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Bimetal‐Catalyzed Cascade Reaction for Efficient Synthesis of N ‐Isopropenyl 1,2,3‐Triazoles via In‐Situ Generated 2‐Azidopropenes
Author(s) -
Liu Zhenhua,
Hao Wenjing,
Liu Zhixian,
Gao Wen,
Zhang Zhihai,
Zhang Yanan,
Li Xiang,
Tong Lili,
Tang Bo
Publication year - 2019
Publication title -
chemistry – an asian journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.18
H-Index - 106
eISSN - 1861-471X
pISSN - 1861-4728
DOI - 10.1002/asia.201900402
Subject(s) - bimetal , cascade , cascade reaction , catalysis , in situ , functional group , combinatorial chemistry , chemistry , yield (engineering) , cleavage (geology) , substrate (aquarium) , bond cleavage , reaction conditions , organic chemistry , materials science , biology , ecology , polymer , chromatography , fracture (geology) , metallurgy , composite material
A bimetal‐catalyzed cascade reaction for the synthesis of N ‐isopropenyl 1,2,3‐triazoles in high yield is reported. This reaction involves the generation of 2‐azidopropenes in situ by C(sp 3 )‐OAr bond cleavage for click reaction and features a broad substrate scope, good functional group tolerance and readily available substrates.