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Aromaticity‐promoted C−F Bond Activation in Rhodium Complex: A Facile Tautomerization
Author(s) -
Shen Ting,
Xie Qiong,
Li Yuanyuan,
Zhu Jun
Publication year - 2019
Publication title -
chemistry – an asian journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.18
H-Index - 106
eISSN - 1861-471X
pISSN - 1861-4728
DOI - 10.1002/asia.201900294
Subject(s) - aromaticity , tautomer , chemistry , fluorine , chemical bond , rhodium , computational chemistry , stereochemistry , molecule , catalysis , organic chemistry
Fluorine is the most electronegative element in the periodic table. Thus, activation of the carbon–fluorine (C−F) bond, the strongest single bond to carbon, has attracted considerable interest from both experimentalists and theoreticians. In comparison with numerous approaches to activate C−F bonds, the aromaticity‐promoted method is less developed. Herein, we demonstrate that the C−F bond activation could be achieved by a facile tautomerization, benefitting from aromaticity, which can stabilize both the transition states and products. Our findings highlight an important application of aromaticity in the C−F bond activation, providing experimentalists with an alternative approach to activate C−F bonds.