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Copper‐Catalyzed Oxidative C−H Bond Functionalization of N‐Allylbenzamide for Regioselective C−N and C−O Bond Formation
Author(s) -
Ranjith Jala,
Krishna Palakodety Radha
Publication year - 2019
Publication title -
chemistry – an asian journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.18
H-Index - 106
eISSN - 1861-471X
pISSN - 1861-4728
DOI - 10.1002/asia.201900192
Subject(s) - regioselectivity , surface modification , catalysis , chemistry , copper , oxidative phosphorylation , combinatorial chemistry , base (topology) , medicinal chemistry , polymer chemistry , organic chemistry , mathematics , mathematical analysis , biochemistry
Copper‐catalyzed oxidative couplings of N‐allylbenzamides for C−N and C−O bond formations have been developed through C−H bond functionalization. To demonstrate the utility of this approach, it was applied to the synthesis of β‐aminoimides and imides. To the best of our knowledge, these are the first examples in which different classes of N‐containing compounds have been directly prepared from the readily available N‐allylbenzamides using an inexpensive catalyst/oxidant/base (CuSO 4 /TBHP/Cs 2 CO 3 ) system.