Premium
Zn II Complexes for Bioimaging and Correlated Applications
Author(s) -
Tian Xiaohe,
Hussain Sajid,
de Pace Cesare,
RuizPérez Lorena,
Battaglia Giuseppe
Publication year - 2019
Publication title -
chemistry – an asian journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.18
H-Index - 106
eISSN - 1861-471X
pISSN - 1861-4728
DOI - 10.1002/asia.201801437
Subject(s) - biocompatible material , zinc , chemistry , metal , nanotechnology , photodynamic therapy , metal ions in aqueous solution , combinatorial chemistry , materials science , organic chemistry , biomedical engineering , medicine
Zinc is a biocompatible element that exists as the second most abundant transition metal ion and an indispensable trace element in the human body. Compared to traditional metal‐organic complexes systems, d 10 metal Zn II complexes not only exhibit a large Stokes shift and good photon stability but also possess strong emission and low cytotoxicity with a relatively small molecular weight. The use of Zn II complexes has emerged in the last decade as a versatile and convenient tool for numerous biological applications, including bioimaging, molecular and protein recognition, as well as photodynamic therapy. Herein, we review recent developments involving Zn II metal complexes applied as specific subcellular compartment imaging probes and their correlated utilizations.