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Photodynamic Therapy Based on Nanoscale Metal–Organic Frameworks: From Material Design to Cancer Nanotherapeutics
Author(s) -
Guan Qun,
Li YanAn,
Li WenYan,
Dong YuBin
Publication year - 2018
Publication title -
chemistry – an asian journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.18
H-Index - 106
eISSN - 1861-471X
pISSN - 1861-4728
DOI - 10.1002/asia.201801221
Subject(s) - photodynamic therapy , nanocarriers , nanotechnology , nanomaterials , photosensitizer , materials science , biocompatibility , nanoscopic scale , metal organic framework , cancer therapy , cancer , chemistry , drug delivery , medicine , photochemistry , organic chemistry , adsorption , metallurgy
Photodynamic therapy (PDT) is a highly effective, noninvasive, highly selective method for cancer treatment. Nanoscale metal–organic frameworks (NMOFs) are a type of crystalline hybrid material composed of metal centers and organic linkers. Owing to their adjustable structure, easy modification, permanent pores, and good biocompatibility, NMOFs, as either nanophotosensitizers or photosensitizer nanocarriers, have been used in PDT. In this article, we summarize the recent progress in MOF‐based nanomaterials for tumor PDT. The MOF‐based nanomaterials might open up new avenues for the fabrication of new types of photosensitizers for PDT.