Premium
Rhodium(III)‐Catalyzed C−H Alkynylation of N ‐Methylsulfoximines
Author(s) -
Wang Tao,
Wang YiNing,
Wang Rui,
Wang XiSheng
Publication year - 2018
Publication title -
chemistry – an asian journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.18
H-Index - 106
eISSN - 1861-471X
pISSN - 1861-4728
DOI - 10.1002/asia.201800889
Subject(s) - alkynylation , rhodium , aryl , catalysis , alkyl , chemistry , functional group , reaction conditions , combinatorial chemistry , medicinal chemistry , stereochemistry , organic chemistry , polymer
A rhodium(III)‐catalyzed direct C−H alkynylation of a wide range of N ‐methylsulfoximines with (bromoethynyl)triisopropylsilane has been developed. This protocol is compatible with both ( S , S )‐diaryl sulfoximines and ( S , S )‐alkyl aryl sulfoximines, and shows mild conditions, and good functional group tolerance. The synthetic utility of this method has been demonstrated by subsequent various transformations of the products.