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Photoredox‐Catalyzed Decarboxylative Oxidation of Arylacetic Acids
Author(s) -
Sakakibara Yota,
Cooper Phillippa,
Murakami Kei,
Itami Kenichiro
Publication year - 2018
Publication title -
chemistry – an asian journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.18
H-Index - 106
eISSN - 1861-471X
pISSN - 1861-4728
DOI - 10.1002/asia.201800529
Subject(s) - photoredox catalysis , catalysis , chemistry , combinatorial chemistry , decarboxylation , organic chemistry , photocatalysis
A photoredox‐catalyzed decarboxylative oxidation of arylacetic acids, which are privileged scaffolds in pharmaceuticals, is reported herein. The established method is operationally simple and a variety of substrates are applicable, providing rapid access to dehomologated bioisosteres of common pharmaceuticals.