Premium
Mild‐Base‐Promoted Arylation of (Hetero)Arenes with Anilines
Author(s) -
Monzón Diego M.,
Santos Tanausú,
PinachoCrisóstomo F.,
Martín Víctor S.,
Carrillo Romen
Publication year - 2018
Publication title -
chemistry – an asian journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.18
H-Index - 106
eISSN - 1861-471X
pISSN - 1861-4728
DOI - 10.1002/asia.201701585
Subject(s) - chemistry , aqueous solution , base (topology) , sodium carbonate , salt (chemistry) , transition metal , free base , combinatorial chemistry , sodium , carbonate , inorganic chemistry , polymer chemistry , organic chemistry , catalysis , mathematical analysis , mathematics
Transition metal‐free radical arylation of heteroarenes is achieved at room temperature by simply adding aqueous sodium carbonate to a solution of the corresponding heteroarene and arenediazonium salt, which can even be formed in situ. Such an easy, inexpensive and mild methodology has been optimized and applied to the expeditious modification of interesting molecular cores like naphthylimide or bisthienylcyclopentenes.