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Front Cover: Single Microbead‐Anchored Fluorescent Immunoassay (SMFIA): A Facile and Versatile Platform Allowing Simultaneous Detection of Multiple Antigens (Chem. Asian J. 22/2017)
Author(s) -
Chen Desheng,
Zhang Xiaobo,
Zhu Liping,
Liu Chenghui,
Li Zhengping
Publication year - 2017
Publication title -
chemistry – an asian journal
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.18
H-Index - 106
eISSN - 1861-471X
pISSN - 1861-4728
DOI - 10.1002/asia.201701396
Subject(s) - microbead (research) , immunoassay , fluorescence , chemistry , nanotechnology , chromatography , materials science , biology , antibody , immunology , optics , physics , biochemistry
Fluorescent immunoassay on a single microbead : A concept of single microbead‐anchored fluorescent immunoassay (SMFIA) has been developed for the facile and sensitive detection of various antigens. Owing to the highly concentrated fluorescence enrichment on a single microbead, the high sensitivity of the SMFIA can fully meet the clinical demand for disease diagnosis just by employing common sandwich immunoreactions without any further signal amplification routes. Furthermore, a fluorescence‐encoding mechanism that allows simultaneous detection of multiple antigens in a single reaction is proposed. More information can be found in the Communication by Chenghui Liu, Zhengping Li et al. on page 2894 in Issue 22, 2017 (DOI: 10.1002/asia.201701245).