Guianolactones A and B, Two Rearranged Pentacyclic Limonoids from the Seeds of Carapa guianensis

Two novel rearranged limonoids, guianolactones A ( 1 ) and B ( 2 ), were isolated from Carapa guianensis Aubl. (Meliaceae) seeds. The structures of 1 and 2 with their absolute configurations were elucidated in detailed examinations using single‐crystal X‐ray diffraction analyses and 2D NMR spectra. Guianolactone A ( 1 ) has a novel 5/6/6/6/6 pentacyclic core including two δ ‐lactone and a tetrahydropyran ring, while guianolactone B ( 2 ) is a novel limonoid with a 6/6/5/6/6 pentacyclic core featuring a δ ‐lactone and a tetrahydrofuran ring.