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One‐Pot Green Synthesis of Nitrogen‐Doped Carbon Quantum Dots for Cell Nucleus Labeling and Copper(II) Detection
Author(s) -
Ci Jiliang,
Tian Ye,
Kuga Shigenori,
Niu Zhongwei,
Wu Min,
Huang Yong
Publication year - 2017
Publication title -
chemistry – an asian journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.18
H-Index - 106
eISSN - 1861-471X
pISSN - 1861-4728
DOI - 10.1002/asia.201700880
Subject(s) - quantum dot , carbon fibers , hydrothermal circulation , quantum yield , fluorescence , nitrogen , copper , particle size , nanoparticle , surface modification , chemistry , yield (engineering) , hydrothermal synthesis , chemical engineering , materials science , nanotechnology , organic chemistry , composite number , composite material , physics , quantum mechanics , engineering
The doping of nitrogen into carbon quantum dots is vitally important for improved fluorescence performance. However, the synthesis of nitrogen‐doped carbon quantum dots (N‐CQDs) is usually conducted under strong acid and high temperature, which results in environmental pollution and energy consumption. Herein, the N‐CQDs were prepared by a mild one‐pot hydrothermal process. The hydrothermal reaction temperature was adjusted to control the particle size, nitrogen/carbon atomic ratio, and quantum yield. The products were water soluble with a narrow particle size distribution and good dispersion stability over a wide pH range. The N‐CQDs could penetrate into the HeLa cell nucleus without any further functionalization. Moreover, the fluorescence of N‐CQDs could be selectively quenched by Cu 2+ , which suggested applications for the detection of Cu 2+ in human plasma.