Premium
Inside Cover: A Scalable and Versatile Synthesis of Oxime‐Based Hormone Dimers and Gels for Sustained Release (Chem. Asian J. 13/2017)
Author(s) -
Bennett Christopher W.,
Collins Joe,
Xiao Zeyun,
Klinger Daniel,
Connal Luke A.
Publication year - 2017
Publication title -
chemistry – an asian journal
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.18
H-Index - 106
eISSN - 1861-471X
pISSN - 1861-4728
DOI - 10.1002/asia.201700698
Subject(s) - oxime , hormone , chemistry , hydrolysis , steroid hormone , steroid , scalability , combinatorial chemistry , computer science , organic chemistry , biochemistry , database
Oxime chemistry , one of the most under‐explored dynamic reactions, was used to create a range of new, hormone‐based, degradable materials. Well‐defined steroid hormone dimers and organogels were produced via a facile and scalable synthesis. Owing to the dynamic nature of the oxime bond, the hormone‐based materials are degradable via acidic hydrolysis and transoximination, representing new materials for the controlled release of steroid hormones. More information can be found in the Communication by Luke A. Connal et al. on page 1456 in Issue 13, 2017 (DOI: 10.1002/asia.201700288).