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Halogen‐Free Synthesis of Carbamates from CO 2 and Amines Using Titanium Alkoxides
Author(s) -
Choi JunChul,
Yuan HaoYu,
Fukaya Norihisa,
Onozawa Syunya,
Zhang Qiao,
Choi Seong Jib,
Yasuda Hiroyuki
Publication year - 2017
Publication title -
chemistry – an asian journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.18
H-Index - 106
eISSN - 1861-471X
pISSN - 1861-4728
DOI - 10.1002/asia.201700465
Subject(s) - aniline , chemistry , halogen , yield (engineering) , titanium , carbon dioxide , titanium dioxide , inorganic chemistry , nuclear chemistry , organic chemistry , carbon fibers , medicinal chemistry , materials science , metallurgy , alkyl , composite number , composite material
A direct synthesis of carbamates from amines and carbon dioxide in the presence of Ti(OR) 4 (R= n Bu ( 1 ), Me ( 2 ), Et ( 3 ), n Pr ( 4 )) was investigated. Aniline was reacted with titanium n ‐butoxide ( 1 ) in the presence of carbon dioxide (5 MPa) to give the corresponding n ‐butyl N ‐phenylcarbamate (BPC) in nearly quantitative yield (99 %) within 20 min. Furthermore, 1 could be regenerated upon reaction with n ‐butanol during water removal. The recovered 1 could then be reused in a subsequent reaction.