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Hyper‐Assembly of Self‐Assembled Glycoclusters Mediated by Specific Carbohydrate–Carbohydrate Interactions
Author(s) -
Yan Gengwei,
Yamaguchi Takumi,
Suzuki Tatsuya,
Yanaka Saeko,
Sato Sota,
Fujita Makoto,
Kato Koichi
Publication year - 2017
Publication title -
chemistry – an asian journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.18
H-Index - 106
eISSN - 1861-471X
pISSN - 1861-4728
DOI - 10.1002/asia.201700202
Subject(s) - chemistry , carbohydrate , trisaccharide , scaffold , self assembly , nanotechnology , aqueous solution , biophysics , biochemistry , organic chemistry , materials science , computer science , biology , database
Hybridization of a self‐assembled, spherical complex with oligosaccharides containing Lewis X, a functional trisaccharide displayed on various cell surfaces, yielded well‐defined glycoclusters. The self‐assembled glycoclusters exhibited homophilic hyper‐assembly in aqueous solution in a Ca 2+ ‐dependent manner through specific carbohydrate–carbohydrate interactions, offering a structural scaffold for functional biomimetic systems.