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A Bioluminogenic Probe for Monitoring Tyrosinase Activity
Author(s) -
Wang Jianguang,
Lee Tae Sup,
Zhang Zhe,
Tung ChingHsuan
Publication year - 2017
Publication title -
chemistry – an asian journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.18
H-Index - 106
eISSN - 1861-471X
pISSN - 1861-4728
DOI - 10.1002/asia.201601659
Subject(s) - tyrosinase , chemistry , endogeny , melanoma , aqueous solution , catechol oxidase , biochemistry , combinatorial chemistry , enzyme , medicine , polyphenol oxidase , organic chemistry , cancer research , peroxidase
A bioluminogenic probe based on luciferin was designed and synthesized to monitor tyrosinase activity. This probe was efficient in assessing tyrosinase activity in a buffered aqueous solution and in measuring endogenous tyrosinase activity in melanoma cells.