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High‐Throughput Synthetic Chemistry Enabled by Organic Solvent Disintegrating Tablet
Author(s) -
Li Tingting,
Xu Lei,
Xing Yanjun,
Xu Bo
Publication year - 2017
Publication title -
chemistry – an asian journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.18
H-Index - 106
eISSN - 1861-471X
pISSN - 1861-4728
DOI - 10.1002/asia.201601487
Subject(s) - reagent , solvent , organic solvent , chemistry , organic chemistry , hazardous waste , organic synthesis , green chemistry , chemical engineering , combinatorial chemistry , nanotechnology , materials science , waste management , reaction mechanism , catalysis , engineering
Synthetic chemistry remains a time‐ and labor‐intensive process of inherent hazardous nature. Our organic solvent disintegrating tablet (O‐Tab) technology has shown potential to make industrial/synthetic chemistry more efficient. As is the case with pharmaceutical tablets, our reagent‐containing O‐Tabs are mechanically strong, but disintegrate rapidly when in contact with reaction media (organic solvents). For O‐Tabs containing sensitive chemicals, they can be further coated to insulate them from air and moisture.