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Cover Picture: Facile Fabrication of Near‐Infrared‐Responsive and Chitosan‐Functionalized Cu 2 Se Nanoparticles for Cancer Photothermal Therapy (Chem. Asian J. 21/2016)
Author(s) -
Liu Zhou,
Chan Leung,
Chen Liyan,
Bai Yan,
Chen Tianfeng
Publication year - 2016
Publication title -
chemistry – an asian journal
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.18
H-Index - 106
eISSN - 1861-471X
pISSN - 1861-4728
DOI - 10.1002/asia.201601224
Subject(s) - photothermal therapy , chitosan , thermostability , cancer therapy , nanoparticle , reactive oxygen species , nanotechnology , chemistry , cancer cell , cancer treatment , photothermal effect , chemotherapy , apoptosis , cancer , materials science , biophysics , cancer research , biochemistry , medicine , biology , surgery , enzyme
Photothermal therapy (PTT) has attracted extensive interest for cancer treatment in the past years. In this study, chitosan (CS)‐modified Cu 2 Se nanoparticles (CS‐Cu 2 Se NPs) were synthesized with the aim to provide cancer chemotherapy and PTT. CS‐Cu 2 Se NPs were found to efficiently convert near‐infrared (NIR) light into heat and displayed excellent thermostability. Upon irradiation with a laser they effectively triggered overproduction of intracellular reactive oxygen species (ROS) that promoted cell apoptosis. Therefore, the as‐synthesized NPs may find use as anticancer agents for chemotherapy‐combined photothermal therapy. More information can be found in the Full Paper by Yan Bai, Tianfeng Chen et al. on page 3032 in Issue 21, 2016 (DOI: 10.1002/asia.201600976).