Silver(I)‐Promoted Radical Sulfonylation of Allyl/Propargyl Alcohols: Efficient Synthesis of γ‐Keto Sulfones | Zendy

Fang Guichun | Zendy; Liu Jianquan | Zendy; Shang Weidong | Zendy; Liu Qun | Zendy; Bi Xihe | Zendy

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Silver(I)‐Promoted Radical Sulfonylation of Allyl/Propargyl Alcohols: Efficient Synthesis of γ‐Keto Sulfones

Author(s) -

Fang Guichun,

Liu Jianquan,

Shang Weidong,

Liu Qun,

Bi Xihe

Publication year - 2016

Publication title -

chemistry – an asian journal

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.18

H-Index - 106

eISSN - 1861-471X

pISSN - 1861-4728

DOI - 10.1002/asia.201601223

Subject(s) - propargyl , chemistry , sulfonyl , organic chemistry , catalysis , medicinal chemistry , sodium , alkyl

An efficient Ag 2 CO 3 ‐promoted sulfonylation of allyl/propargyl alcohols with sodium sulfinates has been developed. The reaction tolerates a wide range of functional groups to deliver γ‐keto sulfones in high yields (up to 93 %). Propargyl alcohols furnished trimerization product 1,3,5‐triaroylbenzenes in the presence of sodium methanesulfinate under the standard conditions. A mechanism involving a sulfonyl radical was suggested.

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