Premium
Inside Cover: Biomineralization of Versatile CuS/Gd 2 O 3 Hybrid Nanoparticles for MR Imaging and Antitumor Photothermal Chemotherapy (Chem. Asian J. 17/2016)
Author(s) -
Zhao HuaiXin,
Wang Hong,
Zou Quan,
Sun ShaoKai,
Yu Chunshui,
Zhang Xuejun,
Fu YanYan
Publication year - 2016
Publication title -
chemistry – an asian journal
Language(s) - English
Resource type - Reports
SCImago Journal Rank - 1.18
H-Index - 106
eISSN - 1861-471X
pISSN - 1861-4728
DOI - 10.1002/asia.201601005
Subject(s) - photothermal therapy , biomineralization , nanoparticle , nanotechnology , materials science , in vivo , drug delivery , chemical engineering , engineering , microbiology and biotechnology , biology
Versatile BSA‐CuS/Gd 2 O 3 hybrid nanoparticles are fabricated by a facile one‐pot albumin‐mediated biomineralization strategy. The obtained multifunctional nanoparticles exhibit strong longitudinal relaxivity, an outstanding photothermal effect, high drug‐loading capacity, and pH/temperature‐responsive drug release. The drug‐loaded BSA‐CuS/Gd 2 O 3 hybrid nanoparticles offer an outstanding synergistic antitumor photothermal chemotherapeutic effect both in vitro and in vivo. This work thus provides technical guidance for designing theranostic agents in a simple way. More information can be found in the Full Paper by Yan‐Yan Fu et al. on page 2458 in Issue 17, 2016 (DOI: 10.1002/asia.201600920).