Rhodium(III)‐Catalyzed Tandem [2+2+2] Annulation–Lactamization of Anilides with Two Alkynoates via Cleavage of Two Adjacent C−H or C−H/C−O bonds | Zendy

Fukui Miho | Zendy; Shibata Yu | Zendy; Hoshino Yuki | Zendy; Sugiyama Haruki | Zendy; Teraoka Kota | Zendy; Uekusa Hidehiro | Zendy; Noguchi Keiichi | Zendy; Tanaka Ken | Zendy

Premium

Rhodium(III)‐Catalyzed Tandem [2+2+2] Annulation–Lactamization of Anilides with Two Alkynoates via Cleavage of Two Adjacent C−H or C−H/C−O bonds

Author(s) -

Fukui Miho,

Shibata Yu,

Hoshino Yuki,

Sugiyama Haruki,

Teraoka Kota,

Uekusa Hidehiro,

Noguchi Keiichi,

Tanaka Ken

Publication year - 2016

Publication title -

chemistry – an asian journal

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.18

H-Index - 106

eISSN - 1861-471X

pISSN - 1861-4728

DOI - 10.1002/asia.201600943

Subject(s) - annulation , chemistry , cleavage (geology) , acetanilide , catalysis , bond cleavage , rhodium , tandem , medicinal chemistry , stereochemistry , ligand (biochemistry) , organic chemistry , biology , receptor , paleontology , biochemistry , materials science , fracture (geology) , composite material

An electron‐deficient Cp E rhodium(III) complex bearing a cyclopentadienyl ligand with two ethyl ester substituents catalyzes the tandem [2+2+2] annulation–lactamization of acetanilides with two alkynoates via cleavage of adjacent two C−H bonds to give densely substituted benzo[ cd ]indolones. The reactions of meta ‐methoxy‐substituted acetanilides with two alkynoates also provided benzo[ cd ]indolones via cleavage of adjacent C−H/C−O bonds. Furthermore, 3,5‐dimethoxyacetanilides reacted with two alkynoates to give dearomatized spiro compounds.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here

Accelerating Research