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KHCO 3 ‐ and DBU‐Promoted Cascade Reaction to Synthesize 3‐Benzyl‐2‐phenylquinolin‐4(1 H)‐ones
Author(s) -
Ma Haojie,
Zhou Xiaoqiang,
Wei DaiDong,
Cao Jinhui,
Shi Chong,
Fan Yuxing,
Huang Guosheng
Publication year - 2016
Publication title -
chemistry – an asian journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.18
H-Index - 106
eISSN - 1861-471X
pISSN - 1861-4728
DOI - 10.1002/asia.201600901
Subject(s) - yield (engineering) , cascade , chemistry , reaction conditions , combinatorial chemistry , cascade reaction , functional group , mechanism (biology) , stereochemistry , catalysis , organic chemistry , materials science , physics , metallurgy , polymer , chromatography , quantum mechanics
A novel and convenient one‐pot route for the synthesis of 3‐benzyl‐2‐phenylquinolin‐4(1 H)‐ones has been developed under transition‐metal‐free conditions. This new strategy features high yield and good functional group tolerance. In addition, a proposed mechanism has been confirmed for this reaction.