Oxidative β‐Csp 3 −H Functionalization of t BuOH: A Selective Radical/Radical Cross‐Coupling Access to β‐Hydroxy Thioethers

An oxidative β‐Csp 3 −H functionalization of tert ‐butanol ( t BuOH) for the construction of C−S bonds through an iodine‐catalyzed Csp 3 −H/S−H coupling was successfully achieved. Different kinds of mercaptans were shown to be good coupling partners, affording the desired products in good yields. This protocol not only offers a novel method for the synthesis of β‐hydroxy thioethers, but also provides an effective strategy for selective radical/radical cross‐coupling.