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A Multifunctional Biomaterial with NIR Long Persistent Phosphorescence, Photothermal Response and Magnetism
Author(s) -
Wu Yiling,
Li Yang,
Qin Xixi,
Qiu Jianrong
Publication year - 2016
Publication title -
chemistry – an asian journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.18
H-Index - 106
eISSN - 1861-471X
pISSN - 1861-4728
DOI - 10.1002/asia.201600569
Subject(s) - photothermal therapy , phosphorescence , persistent luminescence , materials science , magnetism , nanotechnology , magnetic resonance imaging , phosphor , biomaterial , biomedical engineering , fluorescence , optoelectronics , luminescence , optics , medicine , radiology , physics , thermoluminescence , quantum mechanics
There are many reports on long persistent phosphors (LPPs) applied in bioimaging. However, there are few reports on LPPs applied in photothermal therapy (PTT), and an integrated system with multiple functions of diagnosis and therapy. In this work, we fabricate effective multifunctional phosphors Zn 3 Ga 2 SnO 8 : Cr 3+ , Nd 3+ , Gd 3+ with NIR persistent phosphorescence, photothermal response and magnetism. Such featured materials can act as NIR optical biolabels and magnetic resonance imaging (MRI) contrast agents for tracking the early cancer cells, but also as photothermal therapeutic agent for killing the cancer cells. This new multifunctional biomaterial is expected to open a new possibility of setting up an advanced imaging‐guided therapy system featuring a high resolution for bioimaging and low side effects for the photothermal ablation of tumors.