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Enantioselective Recognition by Chiral Supramolecular Gels
Author(s) -
Zhang Li,
Jin Qingxian,
Liu Minghua
Publication year - 2016
Publication title -
chemistry – an asian journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.18
H-Index - 106
eISSN - 1861-471X
pISSN - 1861-4728
DOI - 10.1002/asia.201600441
Subject(s) - enantioselective synthesis , supramolecular chemistry , molecular recognition , materials science , non covalent interactions , molecule , combinatorial chemistry , nanotechnology , chemistry , organic chemistry , hydrogen bond , catalysis
Chiral supramolecular gels, in which small organic molecules self‐assemble into chiral nanostructures and entangle each other to immobilize solvents through various noncovalent interactions, can work as a matrix for enantioselective recognition on chiral analytes. Through gelation and the formation of well‐defined nanostructures, the chiral sense of the component molecules can be accumulated or amplified, and thus, the enantioselective recognition ability can be enhanced. Furthermore, a chiral microenvironment formed in the gel networks could provide additional stereochemical recognition geometry and attribute to efficient recognition. In this focus review, enantioselective recognition on chiral analytes through chiral supramolecular gels, with either amplified signals or the gel–sol phase transition, is discussed. This review is expected to provide useful insights into the design and fabrication of supramolecular gel systems with chiral features and high enantioselectivity.