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Amine‐bis(phenolate) Iron(III)‐Catalyzed Formal Hydroamination of Olefins
Author(s) -
Zhu Kailong,
Shaver Michael P.,
Thomas Stephen P.
Publication year - 2016
Publication title -
chemistry – an asian journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.18
H-Index - 106
eISSN - 1861-471X
pISSN - 1861-4728
DOI - 10.1002/asia.201501098
Subject(s) - hydroamination , amine gas treating , catalysis , silane , chemistry , reaction conditions , combinatorial chemistry , organic chemistry
Abstract A practical synthesis of highly functionalized amines by the formal hydroamination reaction of alkenes with nitroarenes catalyzed by an air stable amine‐bis(phenolate) iron(III) complex is reported. The reaction uses an easily handled silane, low catalyst loadings, and mild reaction conditions. A wide range of substrates are transformed with synthetically useful yields (21 examples).