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Facile Synthesis of Functionalized Carbene Metal Complexes from Coordinated Isonitriles
Author(s) -
Lothschütz Christian,
Wurm Thomas,
Zeiler Anna,
Freiherr v. Falkenhausen Alexander,
Rudolph Matthias,
Rominger Frank,
Hashmi A. Stephen K.
Publication year - 2016
Publication title -
chemistry – an asian journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.18
H-Index - 106
eISSN - 1861-471X
pISSN - 1861-4728
DOI - 10.1002/asia.201500353
Subject(s) - carbene , metal , combinatorial chemistry , chemistry , nanotechnology , materials science , organic chemistry , catalysis
The scope and limitations of the isonitrile‐based NHC template synthesis were investigated with a series of precursors containing a nucleophilic amine in combination with tethered electrophiles. In the case of alkynes and phosphonic esters as electrophiles no ring closure was observed and new functionalized NAC gold complexes were obtained. By the use of unsaturated esters and phosphonic esters as Michael acceptors in the amine precursors, ester‐modified gold and palladium NHC complexes were accessible in high efficiency.