A H + /Ag +  Dual‐Target Responsive Label‐Free Light‐Up Probe Based on a DNA Triplex | Zendy

Xu Lijun | Zendy; Guo Yahui | Zendy; Wang Jine | Zendy; Zhou Lu | Zendy; Zhang Yuanyuan | Zendy; Hong Shanni | Zendy; Wang Zhili | Zendy; Zhang Jianye | Zendy; Pei Renjun | Zendy

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A H + /Ag + Dual‐Target Responsive Label‐Free Light‐Up Probe Based on a DNA Triplex

Author(s) -

Xu Lijun,

Guo Yahui,

Wang Jine,

Zhou Lu,

Zhang Yuanyuan,

Hong Shanni,

Wang Zhili,

Zhang Jianye,

Pei Renjun

Publication year - 2015

Publication title -

chemistry – an asian journal

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 1.18

H-Index - 106

eISSN - 1861-471X

pISSN - 1861-4728

DOI - 10.1002/asia.201500001

Subject(s) - fluorescence , ion , selectivity , dna , intercalation (chemistry) , logic gate , materials science , chemistry , photochemistry , optoelectronics , analytical chemistry (journal) , inorganic chemistry , physics , optics , electronic engineering , chromatography , engineering , biochemistry , organic chemistry , catalysis

We developed a dual‐target responsive sensor for label‐free light‐up fluorescent detection of protons (H + ) and silver ions (Ag + ) using an “OR′′ logic gate. Berberine, a cost‐effective and non‐toxic indicator, partially intercalates the formed triplex DNA in the presence of H + or Ag + , generating enhanced fluorescence. The designed Ag + probe has high selectivity and desirable sensitivity, which is necessary for practical use. The robust ”OR“ logic gate is capable of a rapid and reversible response to the H + and/or Ag + inputs.

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