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An Iminocoumarin Sulfonamide Based Turn‐On Fluorescent Probe for the Detection of Biothiols in Aqueous Solution
Author(s) -
Yang YanLing,
Zhang FuMing,
Wang YaWen,
Zhang BaoXin,
Fang Ran,
Fang JianGuo,
Peng Yu
Publication year - 2015
Publication title -
chemistry – an asian journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.18
H-Index - 106
eISSN - 1861-471X
pISSN - 1861-4728
DOI - 10.1002/asia.201403056
Subject(s) - fluorescence , chemistry , sulfonamide , turn (biochemistry) , phosphate buffered saline , aqueous solution , cascade , combinatorial chemistry , chromatography , organic chemistry , biochemistry , optics , physics
A new chemodosimeter for the highly selective sensing and imaging of biothiols was designed and realized in phosphate‐buffered saline solution at pH 7.4 through a fluorescence “off–on” response. A unique mechanism featuring a two‐step cascade (biothiols→H 2 O) sequence for this remarkable recognition is disclosed for the first time.