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Hybrid Ruthenium ROMP Catalysts Based on an Engineered Variant of β‐Barrel Protein FhuA ΔCVF tev : Effect of Spacer Length
Author(s) -
Sauer Daniel F.,
Bocola Marco,
Broglia Claudio,
Arlt Marcus,
Zhu LeiLei,
Brocker Melanie,
Schwaneberg Ulrich,
Okuda Jun
Publication year - 2015
Publication title -
chemistry – an asian journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.18
H-Index - 106
eISSN - 1861-471X
pISSN - 1861-4728
DOI - 10.1002/asia.201403005
Subject(s) - romp , ruthenium , carbene , polymerization , catalysis , metathesis , covalent bond , polymer chemistry , derivative (finance) , chemistry , olefin fiber , barrel (horology) , cysteine , grubbs' catalyst , polymer , materials science , organic chemistry , composite material , financial economics , economics , enzyme
A biohybrid ring‐opening olefin metathesis polymerization catalyst based on the reengineered β‐barrel protein FhuA ΔCVF tev was chemically modified with respect to the covalently anchored Grubbs–Hoveyda type catalyst. Shortening of the spacer (1,3‐propanediyl to methylene) between the N‐heterocyclic carbene ligand and the cysteine site 545 increased the ROMP activity toward a water‐soluble 7‐oxanorbornene derivative. The cis / trans ratio of the double bond in the polymer was influenced by the hybrid catalyst.