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Back Picture: Ion‐Transfer Electrochemistry of Rat Amylin at the Water–Organogel Microinterface Array and Its Selective Detection in a Protein Mixture (Chem. Asian J. 9/2013)
Author(s) -
Alvarez de Eulate Eva,
O'Sullivan Shane,
Fletcher Sharon,
Newsholme Philip,
Arrigan Damien W. M.
Publication year - 2013
Publication title -
chemistry – an asian journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.18
H-Index - 106
eISSN - 1861-471X
pISSN - 1861-4728
DOI - 10.1002/asia.201390033
Subject(s) - amylin , electrochemistry , chemistry , combinatorial chemistry , electrode , biology , islet , insulin , endocrinology
Electrochemistry The behavior of proteins and polypeptides at electrified aqueousorganic interfaces is of benefit in label‐free detection strategies. In their Full Paper on page 2096 ff. , featured on the Back Cover, Damien W. M. Arrigan et al. report the detection of rat amylin by applying a potential difference across an oilwater interface, thereby causing the molecule to transfer from one phase to another and resulting in a current signal. At physiological pH, rat amylin was selectively detected in the presence of a protein mixture, thus illustrating the bioanalytical possibilities for this electrochemical behavior.