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Switchable Substrates for Analyzing and Engineering Cellular Functions
Author(s) -
Nakanishi Jun
Publication year - 2014
Publication title -
chemistry – an asian journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.18
H-Index - 106
eISSN - 1861-471X
pISSN - 1861-4728
DOI - 10.1002/asia.201301325
Subject(s) - extracellular , nanotechnology , computer science , tissue engineering , extracellular matrix , materials science , microbiology and biotechnology , biology , engineering , biomedical engineering
Abstract Cellular activity is highly dependent on the extracellular environment, which is composed of surrounding cells and extracellular matrices. This focus review summarizes recent advances in chemically and physically engineered switchable substrates designed to control such cellular microenvironments by application of an external stimulus. Special attention is given to their molecular design, switching strategies, and representative examples for bioanalytical and biomedical applications .