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Iridium‐ and Rhodium‐Catalyzed Dehydrogenative Silylations of C(sp 3 )H Bonds Adjacent to a Nitrogen Atom Using Hydrosilanes
Author(s) -
Mita Tsuyoshi,
Michigami Kenichi,
Sato Yoshihiro
Publication year - 2013
Publication title -
chemistry – an asian journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.18
H-Index - 106
eISSN - 1861-471X
pISSN - 1861-4728
DOI - 10.1002/asia.201300930
Subject(s) - rhodium , iridium , catalysis , chemistry , pyridine , norbornene , nitrogen atom , reagent , medicinal chemistry , combinatorial chemistry , photochemistry , organic chemistry , group (periodic table) , polymerization , polymer
Now that is just silylated : In the presence of iridium or rhodium catalysts, C(sp 3 )H bonds adjacent to a nitrogen atom were silylated by the aid of a pyridine‐directing group. In iridium catalysis, a hydrogen‐trapping reagent such as norbornene or tert ‐butylethylene, which is usually required in late transition‐metal‐catalyzed dehydrogenative coupling reactions, was not required. In rhodium catalysis, however, 1 equivalent of COD (1,5‐cyclooctadiene) was necessary to induce higher conversion.