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Nanoelectronics Meets Biology: From New Nanoscale Devices for Live‐Cell Recording to 3D Innervated Tissues
Author(s) -
Duan Xiaojie,
Lieber Charles M.
Publication year - 2013
Publication title -
chemistry – an asian journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.18
H-Index - 106
eISSN - 1861-471X
pISSN - 1861-4728
DOI - 10.1002/asia.201300630
Subject(s) - nanoelectronics , nanotechnology , nanoscopic scale , biology , microbiology and biotechnology , materials science
High spatiotemporal resolution interfaces between electrical sensors and biological systems , from single live cells to tissues, is crucial for many areas, including fundamental biophysical studies as well as medical monitoring and intervention. Herein, we summarize recent progress in the development and application of novel nanoscale devices for intracellular electrical recording of action potentials and the effort of merging electronic and biological systems seamlessly in three dimensions by using macroporous nanoelectronic scaffolds. The uniqueness of these nanoscale devices for minimally invasive, large‐scale, high spatial resolution, and three‐dimensional neural activity mapping are highlighted.