Premium
Synthesis of Allyl Allenes through Three‐Component Cross‐Coupling Reaction of N‐ Tosylhydrazones, Terminal Alkynes, and Allyl Halides
Author(s) -
Ye Fei,
Hossain Mohammad Lokman,
Xu Yan,
Ma Xiaoshen,
Xiao Qing,
Zhang Yan,
Wang Jianbo
Publication year - 2013
Publication title -
chemistry – an asian journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.18
H-Index - 106
eISSN - 1861-471X
pISSN - 1861-4728
DOI - 10.1002/asia.201300340
Subject(s) - terminal (telecommunication) , component (thermodynamics) , chemistry , carbene , halide , medicinal chemistry , combinatorial chemistry , computer science , catalysis , organic chemistry , physics , computer network , thermodynamics
Three's a crowd : Tri‐ and tetrasubstituted allyl allenes can be easily accessed by this Cu I ‐catalyzed three‐component coupling reaction of N ‐tosylhydrazones, terminal alkynes, and allyl halides. The reaction proceeds through a mechanism involving copper carbene migratory insertion.