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[Fe]‐Hydrogenase and Models that Contain IronAcyl Ligation
Author(s) -
Schultz Katherine M.,
Chen Dafa,
Hu Xile
Publication year - 2013
Publication title -
chemistry – an asian journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.18
H-Index - 106
eISSN - 1861-471X
pISSN - 1861-4728
DOI - 10.1002/asia.201300232
Subject(s) - hydrogenase , enzyme , substrate (aquarium) , chemistry , active site , biochemistry , combinatorial chemistry , biology , ecology
[Fe]‐hydrogenase is a newly characterized type of hydrogenase. This enzyme heterolytically splits hydrogen in the presence of a natural substrate. The active site of the enzyme contains a mono‐iron complex with intriguing ironacyl ligation. Several groups have recently developed ironacyl complexes as synthetic models of [Fe]‐hydrogenase. This Focus Review summarizes the studies of this enzyme and its model compounds, with an emphasis on our own research in this area.