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Combining Oxidative N‐Heterocyclic Carbene Catalysis with Click Chemistry: A Facile One‐Pot Approach to 1,2,3‐Triazole Derivatives
Author(s) -
Ramanjaneyulu B. T.,
Reddy Virsinha,
Arde Panjab,
Mahesh Sriram,
Anand R. Vijaya
Publication year - 2013
Publication title -
chemistry – an asian journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.18
H-Index - 106
eISSN - 1861-471X
pISSN - 1861-4728
DOI - 10.1002/asia.201300138
Subject(s) - carbene , click chemistry , propargyl , chemistry , triazole , catalysis , combinatorial chemistry , organic chemistry , oxidative phosphorylation , 1,2,3 triazole , biochemistry
A combination of the oxidative N‐heterocyclic carbene catalysis and click chemistry has been explored for the direct, one‐pot synthesis of 1,2,3‐triazole derivatives from aromatic aldehydes. This procedure was found to be very efficient and a variety of 1,2,3‐triazole derivatives could be accessed through their corresponding propargyl esters in moderate‐to‐good yields under mild conditions.