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Efficient and Selective Synthesis of α,β‐Epoxy‐γ‐Butyrolactones from 2‐Peroxy‐1,4‐Dicarbonyl Compounds
Author(s) -
Liu Kaisheng,
Li Yuanming,
Liu Weiping,
Zheng Xiaojian,
Zong Zhenzhen,
Li Zhiping
Publication year - 2013
Publication title -
chemistry – an asian journal
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.18
H-Index - 106
eISSN - 1861-471X
pISSN - 1861-4728
DOI - 10.1002/asia.201200973
Subject(s) - epoxy , nucleophile , amine gas treating , chemistry , organic chemistry , catalysis , combinatorial chemistry
2 become 1: α,β‐Epoxy‐γ‐butyrolactones were synthesized efficiently and selectively through the nucleophilic cyclization of cis ‐α‐ester‐β‐keto epoxides, which were obtained by an amine‐catalyzed diasteroselective cyclization of 2‐peroxy‐1,4‐dicarbonyl compounds under mild reaction conditions.